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Alterations in mRNA 3′UTR isoform abundance accompany gene expression changes in human Huntington's disease brains

The huntingtin gene has two mRNA isoforms that differ in their 3′UTR length. The relationship of these isoforms with Huntington's disease is not established. We provide evidence that the abundance of huntingtin 3′UTR isoforms differs between patient and control neural stem cells, fibroblasts, m...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Romo, Lindsay, Ashar-Patel, Ami, Pfister, Edith, Aronin, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625827/
https://ncbi.nlm.nih.gov/pubmed/28954224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.009
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