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Alterations in mRNA 3′UTR isoform abundance accompany gene expression changes in human Huntington's disease brains

The huntingtin gene has two mRNA isoforms that differ in their 3′UTR length. The relationship of these isoforms with Huntington's disease is not established. We provide evidence that the abundance of huntingtin 3′UTR isoforms differs between patient and control neural stem cells, fibroblasts, m...

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Publicat a:Cell Rep
Autors principals: Romo, Lindsay, Ashar-Patel, Ami, Pfister, Edith, Aronin, Neil
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625827/
https://ncbi.nlm.nih.gov/pubmed/28954224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.009
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