Resistance to Imatinib in Patients with Chronic Myelogenous Leukemia and the Splice Variant BCR-ABL1(35INS)

PURPOSE: In patients with chronic myelogenous leukemia (CML), point mutations in the BCR-ABL1 kinase domain are the most common cause of treatment failure with a tyrosine kinase inhibitor (TKI). It is not clear whether the splice variant BCR-ABL1(35INS) is also associated with treatment failure. PAT...

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Vydáno v:Leuk Res
Hlavní autoři: Berman, Ellin, Jhanwar, Suresh, Hedvat, Cyrus, Arcila, Maria E., Wahab, Omar Abdel-, Levine, Ross, Maloy, Molly, Ma, Wanlong, Albitar, Maher
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625826/
https://ncbi.nlm.nih.gov/pubmed/27658269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2016.08.006
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