A carregar...
ENHANCED AND SELECTIVE KILLING OF CHRONIC MYELOGENOUS LEUKEMIA CELLS WITH AN ENGINEERED BCR-ABL BINDING PROTEIN AND IMATINIB
The oncoprotein Bcr-Abl stimulates pro-survival pathways and suppresses apoptosis from its exclusively cytoplasmic locale, but when targeted to the mitochondrial compartment of leukemia cells, Bcr-Abl was potently cytotoxic. Therefore, we designed a protein construct to act as a mitochondrial chaper...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529210/ https://ncbi.nlm.nih.gov/pubmed/22957899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3003539 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|