Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy

Chronic myelogenous leukemia (CML) is effectively treated with imatinib mesylate (IM), a small molecule inhibitor of the BCR-ABL tyrosine kinase that is expressed in the entire hematopoietic compartment including stem cells (HSC) and progenitors in CML patients. While IM induces disease remission, i...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Abe, Akihiro, Minami, Yosuke, Hayakawa, Fumihiko, Kitamura, Kunio, Nomura, Yuka, Murata, Makoto, Katsumi, Akira, Kiyoi, Hitoshi, Jamieson, Catriona H. M., Wang, Jean Y. J., Naoe, Tomoki
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626150/
https://ncbi.nlm.nih.gov/pubmed/19039626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-008-0221-1
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk