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The Ins and Outs of Bcr-Abl Inhibition

The development of inhibitors against Abl has changed the landscape for the treatment of chronic myelogenous leukemia (CML) and cancer in general. Beginning with the monumental discovery and approval of imatinib for CML, a second generation of inhibitors, nilotinib and dasatinib, has now gained appr...

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Autores principales: Reddy, E. Premkumar, Aggarwal, Aneel K.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513788/
https://ncbi.nlm.nih.gov/pubmed/23226582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912462126
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