Characterisation of the cancer-associated glucocorticoid system: key role of 11β-hydroxysteroid dehydrogenase type 2

BACKGROUND: Recent studies have shown that production of cortisol not only takes place in several non-adrenal peripheral tissues such as epithelial cells but, also, the local inter-conversion between cortisone and cortisol is regulated by the 11β-hydroxysteroid dehydrogenases (11β-HSDs). However, li...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Cirillo, Nicola, Morgan, David J, Pedicillo, Maria Carmela, Celentano, Antonio, Lo Muzio, Lorenzo, McCullough, Michael J, Prime, Stephen S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625663/
https://ncbi.nlm.nih.gov/pubmed/28797028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.243
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