Aberrant Methylation of APAF-1 Gene in Acute Myeloid Leukemia Patients

Background: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder characterized by immature myeloid cell proliferation and bone marrow failure. Various genetic and epigenetic factors have been found to be influential in such patients. Methylation silencing of APAF-1, a putative tumor suppr...

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Detaylı Bibliyografya
Yayımlandı:Int J Hematol Oncol Stem Cell Res
Asıl Yazarlar: Rostami, Shahrbano, Nadali, Fatemeh, Alibakhshi, Reza, Zaker, Farhad, Nasiri, Nahid, Payandeh, Mehrdad, Chahardouli, Bahram, Maleki, Ali
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625473/
https://ncbi.nlm.nih.gov/pubmed/28989589
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