Aberrant Methylation of APAF-1 Gene in Acute Myeloid Leukemia Patients

Background: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder characterized by immature myeloid cell proliferation and bone marrow failure. Various genetic and epigenetic factors have been found to be influential in such patients. Methylation silencing of APAF-1, a putative tumor suppr...

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Dades bibliogràfiques
Publicat a:Int J Hematol Oncol Stem Cell Res
Autors principals: Rostami, Shahrbano, Nadali, Fatemeh, Alibakhshi, Reza, Zaker, Farhad, Nasiri, Nahid, Payandeh, Mehrdad, Chahardouli, Bahram, Maleki, Ali
Format: Artigo
Idioma:Inglês
Publicat: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625473/
https://ncbi.nlm.nih.gov/pubmed/28989589
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