Aberrant Methylation of APAF-1 Gene in Acute Myeloid Leukemia Patients

Background: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder characterized by immature myeloid cell proliferation and bone marrow failure. Various genetic and epigenetic factors have been found to be influential in such patients. Methylation silencing of APAF-1, a putative tumor suppr...

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Bibliografske podrobnosti
izdano v:Int J Hematol Oncol Stem Cell Res
Main Authors: Rostami, Shahrbano, Nadali, Fatemeh, Alibakhshi, Reza, Zaker, Farhad, Nasiri, Nahid, Payandeh, Mehrdad, Chahardouli, Bahram, Maleki, Ali
Format: Artigo
Jezik:Inglês
Izdano: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625473/
https://ncbi.nlm.nih.gov/pubmed/28989589
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