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Aberrant Methylation of APAF-1 Gene in Acute Myeloid Leukemia Patients
Background: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder characterized by immature myeloid cell proliferation and bone marrow failure. Various genetic and epigenetic factors have been found to be influential in such patients. Methylation silencing of APAF-1, a putative tumor suppr...
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Publicado no: | Int J Hematol Oncol Stem Cell Res |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5625473/ https://ncbi.nlm.nih.gov/pubmed/28989589 |
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