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IL-4 Induces IL17Rb Gene Transcription in Monocytic Cells with Coordinate Autocrine IL-25 Signaling

IL-25 and IL-4 signaling in the setting of infection or allergic responses can drive Type 2 inflammation. IL-25 requires the IL-17 receptor B (IL-17Rb) to mediate signaling through nuclear factor κ B (NF-κB) transcriptional activation. Despite the known coexistence of these two cytokines in the Type...

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Vydáno v:Am J Respir Cell Mol Biol
Hlavní autoři: Weathington, Nathaniel M., Kanth, Shreya M., Gong, Qiaoke, Londino, James, Hoji, Akihiko, Rojas, Mauricio, Trudeau, John, Wenzel, Sally, Mallampalli, Rama K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625225/
https://ncbi.nlm.nih.gov/pubmed/28421819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0316OC
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