Cardiac fibroblast transcriptome analyses support a role for interferogenic, profibrotic, and inflammatory genes in anti-SSA/Ro-associated congenital heart block

The signature lesion of SSA/Ro autoantibody-associated congenital heart block (CHB) is fibrosis and a macrophage infiltrate, supporting an experimental focus on cues influencing the fibroblast component. The transcriptomes of human fetal cardiac fibroblasts were analyzed using two complementary appr...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Clancy, Robert M., Markham, Androo J., Jackson, Tanisha, Rasmussen, Sara E., Blumenberg, Miroslav, Buyon, Jill P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625175/
https://ncbi.nlm.nih.gov/pubmed/28626076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00256.2017
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