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Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors
Diallyl sulfide (DAS), a selective inhibitor of CYP2E1, has shown protective effects against alcohol‐ and acetaminophen‐induced hepatotoxicity in many studies. However, DAS is also a CYP2E1 substrate that on metabolism produces toxic metabolites and causes cytotoxicity. The objective of this study w...
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| Publicado en: | Pharmacol Res Perspect |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5625166/ https://ncbi.nlm.nih.gov/pubmed/28971616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.362 |
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