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Kinetic studies of novel inhibitors of endomorphin degrading enzymes
Endomorphins (EMs), two endogenous μ-opioid receptor selective ligands, are attractive lead compounds for opioid-based pain management studies. However, these peptides are quickly degraded by peptidases, in particular by dipeptidylpeptidase IV (DPP IV) and aminopeptidase M (APM). Targeting enzymatic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer-Verlag
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359464/ https://ncbi.nlm.nih.gov/pubmed/22707871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-011-9666-5 |
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