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Therapeutic potential of nuclear receptor agonists in Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by an extensive accumulation of amyloid-β (Aβ) peptide, which triggers a set of deleterious processes, including synaptic dysfunction, inflammation, and neuronal injury, leading to neuronal loss and cognitive impairment. A large body of evidence supports tha...

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Bibliographische Detailangaben
Veröffentlicht in:J Lipid Res
Hauptverfasser: Moutinho, Miguel, Landreth, Gary E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625128/
https://ncbi.nlm.nih.gov/pubmed/28264880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R075556
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