Redox-dependent dimerization of p38α mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3

The kinase p38α MAPK (p38α) plays a pivotal role in many biological processes. p38α is activated by canonical upstream kinases that phosphorylate the activation region. The purpose of our study was to determine whether such activation may depend on redox-sensing cysteines within p38α. p38α was activ...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Bassi, Rekha, Burgoyne, Joseph R., DeNicola, Gian F., Rudyk, Olena, DeSantis, Vittorio, Charles, Rebecca L., Eaton, Philip, Marber, Michael S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2017
Aiheet:
Signal Transduction
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625047/
https://ncbi.nlm.nih.gov/pubmed/28739872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.785410
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