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Coupled reactions by coupled enzymes: alcohol to lactone cascade with alcohol dehydrogenase–cyclohexanone monooxygenase fusions

The combination of redox enzymes for redox-neutral cascade reactions has received increasing appreciation. An example is the combination of an alcohol dehydrogenase (ADH) with a cyclohexanone monooxygenase (CHMO). The ADH can use NADP(+) to oxidize cyclohexanol to form cyclohexanone and NADPH. Both...

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發表在:Appl Microbiol Biotechnol
Main Authors: Aalbers, Friso S., Fraaije, Marco W.
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624969/
https://ncbi.nlm.nih.gov/pubmed/28916997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-017-8501-4
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