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Schwann cells promote post-traumatic nerve inflammation and neuropathic pain through MHC class II

The activation of T helper cells requires antigens to be exposed on the surface of antigen presenting cells (APCs) via MHC class II (MHC-II) molecules. Expression of MHC-II is generally limited to professional APCs, but other cell types can express MHC-II under inflammatory conditions. However, the...

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Pubblicato in:Sci Rep
Autori principali: Hartlehnert, Maike, Derksen, Angelika, Hagenacker, Tim, Kindermann, David, Schäfers, Maria, Pawlak, Mathias, Kieseier, Bernd C., Meyer zu Horste, Gerd
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624882/
https://ncbi.nlm.nih.gov/pubmed/28970572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12744-2
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