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Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling
BACKGROUND: The lysophospholipids sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) are pleiotropic signaling molecules with a broad range of physiological functions. Targeting the S1P(1) receptor on lymphocytes with the immunomodulatory drug fingolimod has proven effective in the treatm...
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| Publicado no: | J Neuroinflammation |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4901498/ https://ncbi.nlm.nih.gov/pubmed/27283020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0612-9 |
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