Quinpramine Ameliorates Rat Experimental Autoimmune Neuritis and Redistributes MHC Class II Molecules

Activation of inflammatory cells is central to the pathogenesis of autoimmune demyelinating diseases of the peripheral nervous system. The novel chimeric compound quinpramine—generated from imipramine and quinacrine—redistributes cholesterol rich membrane domains to intracellular compartments. We st...

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Bibliografiska uppgifter
Huvudupphovsmän: Meyer zu Hörste, Gerd, Mausberg, Anne K., Müller, Johanna I., Lehmann, Helmar C., Löber, Stefan, Gmeiner, Peter, Hartung, Hans-Peter, Stüve, Olaf, Korth, Carsten, Kieseier, Bernd C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116892/
https://ncbi.nlm.nih.gov/pubmed/21698177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021223
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