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Positive Germline Selection in Pedigrees With Multiple Endocrine Neoplasia Type 2 Carrying V804M Mutation in the RET Gene

BACKGROUND: Multiple endocrine neoplasia (MEN) type 2 is an autosomal dominant cancer syndrome associated with the development of thyroid cancer and tumors or hyperplasia in other endocrine organs. It is caused by mutations in the RET gene and can be phenotypically classified into MEN types 2A and 2...

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Bibliographische Detailangaben
Veröffentlicht in:World J Oncol
Hauptverfasser: Peddareddygari, Leema Reddy, Fay, Angela Musial, Shifrin, Alexander L., Grewal, Raji P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elmer Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624651/
https://ncbi.nlm.nih.gov/pubmed/28983374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14740/wjon970e
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