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Identification of Novel Mutations in Spatacsin and Apolipoprotein B Genes in a Patient with Spastic Paraplegia and Hypobetalipoproteinemia

Complicated hereditary spastic paraplegia (HSP) presents with complex neurological and nonneurological manifestations. We report a patient with autosomal recessive (AR) HSP in whom laboratory investigations revealed hypobetalipoproteinemia raising the possibility of a shared pathophysiology of these...

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Detalhes bibliográficos
Publicado no:Case Rep Genet
Main Authors: Peddareddygari, Leema Reddy, Grewal, Raji P.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439468/
https://ncbi.nlm.nih.gov/pubmed/26064709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/219691
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