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Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia
Stroke causes severe neuronal damage as disrupted cerebral blood flow starves neurons of oxygen and glucose. The hypoxia inducible factors (HIF-1α and HIF-2α) orchestrate oxygen homeostasis and regulate specific aspects of hypoxic adaptation. Here we show the importance of HIF-2α dependant signallin...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5624621/ https://ncbi.nlm.nih.gov/pubmed/28968430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185664 |
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