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dCas9-mediated transcriptional activation of tissue inhibitor of metalloproteinases

Selective gene activation with the dCas9 (deactivated clustered regularly interspaced short palindromic repeats [CRISPR] associated protein 9)/CRISPR targeting of a transcriptional activator effector is now well established. However, the optimal targeting of guide RNA (gRNA) for a given gene is larg...

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Bibliografische gegevens
Gepubliceerd in:Metalloproteinases Med
Hoofdauteurs: Duellman, Tyler, Doll, Andrea, Chen, Xi, Wakamiya, Rie, Yang, Jay
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624544/
https://ncbi.nlm.nih.gov/pubmed/28979918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/MNM.S146752
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