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dCas9-mediated transcriptional activation of tissue inhibitor of metalloproteinases

Selective gene activation with the dCas9 (deactivated clustered regularly interspaced short palindromic repeats [CRISPR] associated protein 9)/CRISPR targeting of a transcriptional activator effector is now well established. However, the optimal targeting of guide RNA (gRNA) for a given gene is larg...

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Bibliografske podrobnosti
izdano v:Metalloproteinases Med
Main Authors: Duellman, Tyler, Doll, Andrea, Chen, Xi, Wakamiya, Rie, Yang, Jay
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624544/
https://ncbi.nlm.nih.gov/pubmed/28979918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/MNM.S146752
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