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Photoinduced, Copper-Catalyzed Decarboxylative C–N Coupling to Generate Protected Amines: An Alternative to the Curtius Rearrangement

The Curtius rearrangement is a classic, powerful method for converting carboxylic acids into protected amines, but its widespread use is impeded by safety issues (the need to handle azides). We have developed an alternative to the Curtius rearrangement that employs a copper catalyst in combination w...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Zhao, Wei, Wurz, Ryan P., Peters, Jonas C., Fu, Gregory C.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624330/
https://ncbi.nlm.nih.gov/pubmed/28841018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07546
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