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Thwarting endogenous stress: BRCA protects against aldehyde toxicity
Homologous recombination (HR) and the Fanconi Anemia (FA) pathways constitute essential repair pathways for DNA damage, which includes DNA double‐stranded breaks (DSB) and inter‐strand cross‐links (ICL), respectively. Germline mutations affecting a single copy of the HR factors BRCA1 and BRCA2 predi...
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| 出版年: | EMBO Mol Med |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5623899/ https://ncbi.nlm.nih.gov/pubmed/28835508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708194 |
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