Brucella Rough Mutant Induce Macrophage Death via Activating IRE1α Pathway of Endoplasmic Reticulum Stress by Enhanced T4SS Secretion

Brucella is a Gram-negative facultative intracellular pathogen that causes the worldwide zoonosis, known as brucellosis. Brucella virulence relies mostly on its ability to invade and replicate within phagocytic cells. The type IV secretion system (T4SS) and lipopolysaccharide are two major Brucella...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Li, Peng, Tian, Mingxing, Bao, Yanqing, Hu, Hai, Liu, Jiameng, Yin, Yi, Ding, Chan, Wang, Shaohui, Yu, Shengqing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623715/
https://ncbi.nlm.nih.gov/pubmed/29021973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00422
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