Brucella Rough Mutant Induce Macrophage Death via Activating IRE1α Pathway of Endoplasmic Reticulum Stress by Enhanced T4SS Secretion

Brucella is a Gram-negative facultative intracellular pathogen that causes the worldwide zoonosis, known as brucellosis. Brucella virulence relies mostly on its ability to invade and replicate within phagocytic cells. The type IV secretion system (T4SS) and lipopolysaccharide are two major Brucella...

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Dades bibliogràfiques
Publicat a:Front Cell Infect Microbiol
Autors principals: Li, Peng, Tian, Mingxing, Bao, Yanqing, Hu, Hai, Liu, Jiameng, Yin, Yi, Ding, Chan, Wang, Shaohui, Yu, Shengqing
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623715/
https://ncbi.nlm.nih.gov/pubmed/29021973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00422
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