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Brevetoxin-2, is a unique inhibitor of the C-terminal redox center of mammalian thioredoxin reductase-1

Karenia brevis, the Florida red tide dinoflagellate produces a suite of neurotoxins known as the brevetoxins. The most abundant of the brevetoxins PbTx-2, was found to inhibit the thioredoxin-thioredoxin reductase system, whereas the PbTx-3 has no effect on this system. On the other hand, PbTx-2 act...

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Bibliografiska uppgifter
I publikationen:Toxicol Appl Pharmacol
Huvudupphovsmän: Chen, Wei, Tuladhar, Anupama, Rolle, Shantelle, Lai, Yanhao, del Rey, Freddy Rodriguez, Zavala, Cristian E., Liu, Yuan, Rein, Kathleen S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623065/
https://ncbi.nlm.nih.gov/pubmed/28551108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2017.05.027
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