Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets

The classical Trx (thioredoxin) system, composed of TR (Trx reductase), Trx and NADPH, defines a major pathway of cellular thiol-based redox regulation. Three TRs have been identified in mammals: (i) cytosolic TR1, (ii) mitochondrial TR3 and (iii) testes-specific TGR (Trx-glutathione reductase). All...

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Autori principali: Turanov, Anton A., Kehr, Sebastian, Marino, Stefano M., Yoo, Min-Hyuk, Carlson, Bradley A., Hatfield, Dolph L., Gladyshev, Vadim N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471089/
https://ncbi.nlm.nih.gov/pubmed/20536427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091378
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