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Novel Carbonyl Analogs of Tamoxifen: Design, Synthesis, and Biological Evaluation
Aim of this work was to provide tamoxifen analogs with enhanced estrogen receptor (ER) binding affinity. Hence, several derivatives were prepared using an efficient triarylethylenes synthetic protocol. The novel compounds bioactivity was evaluated through the determination of their receptor binding...
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| Publicado no: | Front Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5622936/ https://ncbi.nlm.nih.gov/pubmed/29018796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00071 |
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