Design, Synthesis, and Antitumor Biological Evaluation of Galaxamide and Its Analogs

Galaxamide, an <i>N</i>-methylated cyclo-pentapeptide containing five <i>D</i>-leucines isolated from <i>Galaxaura filamentosa</i>, has shown significant antitumor activity. This unique cyclo-pentapeptide offered a fresh skeleton for structural modifications. Herein, galaxamide and its 23 analogs (<...

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Bibliografske podrobnosti

Principais autores:	Yanyan Guo, Huixia Fan, Zhiqiang Luo, Jian Yang, Guodu Liu
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2025-05-01
Serija:	Molecules
Teme:	galaxamide cyclopeptide liquid-phase peptide synthesis marine natural product antitumor agent
Online dostop:	https://www.mdpi.com/1420-3049/30/11/2362
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