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Hypoxia preconditioning promotes cardiac stem cell survival and cardiogenic differentiation in vitro involving activation of the HIF-1α/apelin/APJ axis
BACKGROUND: Cardiac stem cells (CSCs) transplantation has been regarded as an optimal therapeutic approach for cardiovascular disease. However, inferior survival and low differentiation efficiency of these cells in the local infarct site reduce their therapeutic efficacy. In this study, we investiga...
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出版年: | Stem Cell Res Ther |
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主要な著者: | , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
BioMed Central
2017
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5622481/ https://ncbi.nlm.nih.gov/pubmed/28962638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0673-4 |
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