Hypoxia preconditioning promotes cardiac stem cell survival and cardiogenic differentiation in vitro involving activation of the HIF-1α/apelin/APJ axis

BACKGROUND: Cardiac stem cells (CSCs) transplantation has been regarded as an optimal therapeutic approach for cardiovascular disease. However, inferior survival and low differentiation efficiency of these cells in the local infarct site reduce their therapeutic efficacy. In this study, we investiga...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Hou, Jingying, Wang, Lei, Long, Huibao, Wu, Hao, Wu, Quanhua, Zhong, Tingting, Chen, Xuxiang, Zhou, Changqing, Guo, Tianzhu, Wang, Tong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622481/
https://ncbi.nlm.nih.gov/pubmed/28962638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0673-4
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