Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils

Autoantibodies directed against citrullinated epitopes of proteins are highly diagnostic of rheumatoid arthritis (RA), and elevated levels of protein citrullination can be found in the joints of patients with RA. Calcium-dependent peptidyl-arginine deiminases (PAD) are the enzymes responsible for ci...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Zhou, Yebin, Chen, Bo, Mittereder, Nanette, Chaerkady, Raghothama, Strain, Martin, An, Ling-Ling, Rahman, Saifur, Ma, Wenting, Low, Choon Pei, Chan, Denice, Neal, Frances, Bingham, Clifton O., Sampson, Kevon, Darrah, Erika, Siegel, Richard M., Hasni, Sarfaraz, Andrade, Felipe, Vousden, Katherine A., Mustelin, Tomas, Sims, Gary P.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622307/
https://ncbi.nlm.nih.gov/pubmed/28993780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01200
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