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Methylation-mediated silencing of miR-124 facilitates chondrogenesis by targeting NFATc1 under hypoxic conditions

Chondrogenic differentiation of mesenchymal stem cells is regulated by many different pathways. Recent studies have established that hypoxia and epigenetic alterations potently affect expression of chondrogenesis marker genes. Sox9 is generally regarded as a master regulator of chondrogenesis and mi...

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Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Gong, Ming, Liang, Tangzhao, Jin, Song, Dai, Xuejun, Zhou, Zhiyu, Gao, Manman, Huang, Sheng, Luo, Jiaquan, Zou, Lijin, Zou, Xuenong
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622255/
https://ncbi.nlm.nih.gov/pubmed/28979686
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