Methylation-mediated silencing of miR-124 facilitates chondrogenesis by targeting NFATc1 under hypoxic conditions

Chondrogenic differentiation of mesenchymal stem cells is regulated by many different pathways. Recent studies have established that hypoxia and epigenetic alterations potently affect expression of chondrogenesis marker genes. Sox9 is generally regarded as a master regulator of chondrogenesis and mi...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Gong, Ming, Liang, Tangzhao, Jin, Song, Dai, Xuejun, Zhou, Zhiyu, Gao, Manman, Huang, Sheng, Luo, Jiaquan, Zou, Lijin, Zou, Xuenong
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622255/
https://ncbi.nlm.nih.gov/pubmed/28979686
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