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Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin
The Cys2/His2-type zinc finger protein Zfp296 has been implicated in stem cell pluripotency and tumor pathogenesis. However, its mechanisms remain elusive. Here, we demonstrated that a Zfp296 deficiency in mice impairs germ-cell development and embryonic growth. Zfp296 was intracellularly localized...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5622089/ https://ncbi.nlm.nih.gov/pubmed/28963472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12772-y |
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