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Functional Analysis of Tcl1 Using Tcl1-Deficient Mouse Embryonic Stem Cells

Tcl1 is highly expressed in embryonic stem (ES) cells, but its expression rapidly decreases following differentiation. To assess Tcl1’s roles in ES cells, we generated Tcl1-deficient and -overexpressing mouse ES cell lines. We found that Tcl1 was neither essential nor sufficient for maintaining the...

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Detalhes bibliográficos
Main Authors: Miyazaki, Tatsushi, Miyazaki, Satsuki, Ashida, Masafumi, Tanaka, Tomofumi, Tashiro, Fumi, Miyazaki, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733782/
https://ncbi.nlm.nih.gov/pubmed/23940776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071645
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