Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo

Synapses are an early pathological target in many neurodegenerative diseases ranging from well-known adult onset conditions such as Alzheimer and Parkinson disease to neurodegenerative conditions of childhood such as spinal muscular atrophy (SMA) and neuronal ceroid lipofuscinosis (NCLs). However, t...

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Udgivet i:Sci Rep
Main Authors: Llavero Hurtado, Maica, Fuller, Heidi R., Wong, Andrew M. S., Eaton, Samantha L., Gillingwater, Thomas H., Pennetta, Giuseppa, Cooper, Jonathan D., Wishart, Thomas M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622084/
https://ncbi.nlm.nih.gov/pubmed/28963550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12603-0
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