Reversal of pathological cardiac hypertrophy via the MEF2-coregulator interface

Cardiac hypertrophy, as a response to hemodynamic stress, is associated with cardiac dysfunction and death, but whether hypertrophy itself represents a pathological process remains unclear. Hypertrophy is driven by changes in myocardial gene expression that require the MEF2 family of DNA-binding tra...

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Gepubliceerd in:JCI Insight
Hoofdauteurs: Wei, Jianqin, Joshi, Shaurya, Speransky, Svetlana, Crowley, Christopher, Jayathilaka, Nimanthi, Lei, Xiao, Wu, Yongqing, Gai, David, Jain, Sumit, Hoosien, Michael, Gao, Yan, Chen, Lin, Bishopric, Nanette H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621875/
https://ncbi.nlm.nih.gov/pubmed/28878124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91068
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