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Repression of miR-142 by p300 and MAPK is required for survival signalling via gp130 during adaptive hypertrophy

An increase in cardiac workload, ultimately resulting in hypertrophy, generates oxidative stress and therefore requires the activation of both survival and growth signal pathways. Here, we wanted to characterize the regulators, targets and mechanistic roles of miR-142, a microRNA (miRNA) negatively...

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Detalhes bibliográficos
Main Authors: Sharma, Salil, Liu, Jing, Wei, Jianqin, Yuan, Huijun, Zhang, Taifang, Bishopric, Nanette H
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407949/
https://ncbi.nlm.nih.gov/pubmed/22367739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200234
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