Not all SCID pigs are created equally: Two independent mutations in the Artemis gene cause Severe Combined Immunodeficiency (SCID) in pigs: Two mutations in the Artemis gene cause SCID in pigs

Mutations in over 30 genes are known to result in impairment of the adaptive immune system, causing a group of disorders collectively known as severe combined immunodeficiency (SCID). SCID disorders are split into groups based on their presence and/or functionality of B, T, and NK cells. Piglets fro...

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Pubblicato in:J Immunol
Autori principali: Waide, Emily H, Dekkers, Jack CM, Ross, Jason W, Rowland, Raymond RR, Wyatt, Carol R, Ewen, Catherine L, Evans, Alyssa B, Thekkoot, Dinesh M, Boddicker, Nicholas J, Serão, Nick VL, Ellinwood, N Matthew, Tuggle, Christopher K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621739/
https://ncbi.nlm.nih.gov/pubmed/26320255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501132
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