Infectivity of GII.4 human norovirus does not differ between T(−)B(−)NK(+) Severe Combined Immunodeficiency (SCID) and non-SCID gnotobiotic pigs, implicating the role of NK cells in mediation of human norovirus infection

Human noroviruses (HuNoVs) are a leading cause of acute gastroenteritis worldwide. It is unclear which arm of the immune system regulates resistance to HuNoV infection. Thus, we studied the pathogenesis of human norovirus (HuNoV) in T(−)B(−)NK(+) Severe Combined Immunodeficiency (SCID) gnotobiotic p...

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Publicado no:Virus Res
Main Authors: Annamalai, Thavamathi, Lu, Zhongyan, Jung, Kwonil, Langel, Stephanie N., Tuggle, Christopher K., Dekkers, Jack C. M., Waide, Emily H., Kandasamy, Sukumar, Saif, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534450/
https://ncbi.nlm.nih.gov/pubmed/31054932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2019.05.002
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