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Defective erythropoiesis caused by mutations of the thyroid hormone receptor α gene
Patients with mutations of the THRA gene exhibit classical features of hypothyroidism, including erythroid disorders. We previously created a mutant mouse expressing a mutated TRα1 (denoted as PV; Thra1(PV/+) mouse) that faithfully reproduces the classical hypothyroidism seen in patients. Using Thra...
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| 發表在: | PLoS Genet |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5621702/ https://ncbi.nlm.nih.gov/pubmed/28910278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006991 |
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