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RNA splicing process analysis for identifying antisense oligonucleotide inhibitors with padlock probe-based isothermal amplification

RNA splicing, which mainly involves two transesterification steps, is a fundamental process of gene expression and its abnormal regulation contributes to serious genetic diseases. Antisense oligonucleotides (ASOs) are genetic control tools that can be used to specifically control genes through alter...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Ren, Xiaojun, Deng, Ruijie, Wang, Lida, Zhang, Kaixiang, Li, Jinghong
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621167/
https://ncbi.nlm.nih.gov/pubmed/28989608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01336a
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