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Visual Detection of Bacterial Pathogens via PNA-Based Padlock Probe Assembly and Isothermal Amplification of DNAzymes

[Image: see text] We have developed a self-reporting isothermal system for visual bacterial pathogen detection with single base resolution. The new DNA diagnostic is based on combination of peptide nucleic acid (PNA) technology, rolling circle amplification (RCA) and DNAzymes. PNAs are used as excee...

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Bibliografiske detaljer
Udgivet i:Anal Chem
Main Authors: Gomez, Anastasia, Miller, Nancy S., Smolina, Irina
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270401/
https://ncbi.nlm.nih.gov/pubmed/25415469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac5018748
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