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RNA splicing process analysis for identifying antisense oligonucleotide inhibitors with padlock probe-based isothermal amplification

RNA splicing, which mainly involves two transesterification steps, is a fundamental process of gene expression and its abnormal regulation contributes to serious genetic diseases. Antisense oligonucleotides (ASOs) are genetic control tools that can be used to specifically control genes through alter...

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Библиографические подробности
Опубликовано в: :Chem Sci
Главные авторы: Ren, Xiaojun, Deng, Ruijie, Wang, Lida, Zhang, Kaixiang, Li, Jinghong
Формат: Artigo
Язык:Inglês
Опубликовано: Royal Society of Chemistry 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621167/
https://ncbi.nlm.nih.gov/pubmed/28989608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01336a
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