Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo

Radiation therapy (RT) is the current standard adjuvant approach for oral squamous cell carcinoma (OSCC) patients. Radioresistance is a major contributor to radiotherapy failure. In this study, we used patient-derived cells and a radiation-resistant cell line in vitro and in vivo for two purposes: e...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yu, Chih-Chia, Hung, Shih-Kai, Lin, Hon-Yi, Chiou, Wen-Yen, Lee, Moon-Sing, Liao, Hui-Fen, Huang, Hsien-Bin, Ho, Hsu-Chueh, Su, Yu-Chieh
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620284/
https://ncbi.nlm.nih.gov/pubmed/28978144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19817
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